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Overweight vs. Obesity: Understanding the Differences and Health Impacts
That said, doctors are now looking beyond BMI to diagnose people who are overweight and have obesity by considering additional factors, such as their waist circumference and where they store excess fat. Where excess fat is stored can have a significant impact on a person’s risk of weight-related health issues, says Francisco Lopez-Jimenez, MD, director of the cardiometabolic program at Mayo Clinic in Rochester, Minnesota.
“Fat stored around the abdomen is more strongly linked to heart disease and diabetes than fat in other areas,” says Dr. Lopez-Jimenez. “Waist-based measurements are a simple way to estimate this risk.”
What Are the Definitions of Overweight and Obesity?
Doctors rely on BMI to determine whether people are overweight or have obesity, but it’s becoming just one of several measurements clinicians can use to diagnose these chronic conditions.
The Role of BMI
Adults with a BMI of 18.5 to 24.9 are considered at a healthy weight. An adult who is 5 feet 9 inches tall has a BMI in this range if they weigh 125 to 168 pounds.
Individuals with a BMI of 25 to 29.9 are considered overweight. An adult who is 5 feet 9 inches tall has a BMI in the overweight range if they weigh 169 to 202 pounds.
Why BMI Is No Longer the Only Metric
Moving Toward Better Measurements
Other measurements can help provide a complete assessment of whether you have an unhealthy weight. Waist circumference is one way to measure excess fat around the midsection, which tends to carry a higher risk of conditions like heart disease and diabetes than excess fat stored on the hips.
Key Differences: Is Obesity a Disease?
A higher BMI and more body fat is the most obvious difference between overweight and obesity, but the definitions and causes of the two chronic conditions can also differ.
How Weight Impacts Long-Term Health
“Obesity isn’t just excess weight,” says Christopher McGowan, MD, an obesity medicine specialist and the senior vice president at Everself, a weight care company with locations throughout the United States. “It’s a chronic inflammatory disease affecting the entire body.”
The Role of Inflammation
The trouble with overweight and obesity isn’t just that one carries excess body fat, but rather the type of fat that accumulates.
Systemic Impact
- Heart Disease Excess fat can affect blood vessels and lead to high blood pressure. It also contributes to other heart disease risk factors, such as high cholesterol, type 2 diabetes, and sleep apnea.
- Type 2 Diabetes Excess fat makes cells more resistant to the effects of insulin, a hormone that moves sugar (glucose) from the bloodstream into cells. It also damages beta cells in the pancreas, which are responsible for making insulin. As a result, blood sugar levels rise.
- Obstructive Sleep Apnea (OSA) Excess fatty tissue in the throat can cover the airway during sleep, leading to repeated pauses in breathing and increasing the risk of OSA. And because a lack of sleep increases levels of the appetite-stimulating hormone ghrelin in the body, OSA can lead to even more weight gain.
- Joint Health Overweight and obesity can also contribute to osteoarthritis, a painful joint condition, in two ways: Fat releases inflammatory chemicals that can cause pain and swelling, and excess weight puts added pressure on the joints.
Metabolic Health
Most people who are overweight or have obesity also exhibit signs of metabolic health issues, such as high blood pressure, high blood sugar, and high cholesterol, all of which increase the risk of chronic disease. Some people manage to avoid these health problems, which doctors sometimes refer to as “metabolically healthy obesity.”
“Metabolically healthy obesity refers to people who have a higher BMI but normal blood sugar, cholesterol, blood pressure, and no clear signs of inflammation or insulin resistance,” says Lopez-Jimenez. “This state is often temporary. Over time, many will develop metabolic abnormalities.”
Even if you’re considered metabolically healthy and feel fine, it’s still important to lose weight, because obesity is a progressive disease, says Lopez-Jimenez.
Current Management and Treatment Options
Nutrition and Lifestyle Changes
The New Era of Medications
If diet and exercise alone aren’t getting you to your weight loss goal, medication may be an option.
Weight loss medications approved by the U.S. Food and Drug Administration (FDA) include:
- diethylpropion (Tenuate)
- liraglutide (Saxenda)
- naltrexone/bupropion (Contrave)
- orforglipron (Foundayo)
- orlistat (Alli)
- phendimetrazine (Bontril)
- phentermine-topiramate (Qsymia)
- semaglutide (Wegovy)
- tirzepatide (Zepbound)
Surgical and Procedural Options
- A BMI of 40 or higher
- A BMI of 35 or higher and a serious weight-related health condition, like type 2 diabetes or heart disease
- A BMI of 30 or higher and type 2 diabetes that’s difficult to control with other treatments
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